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The obtained results indicate that
2023-09-04

The obtained results indicate that even when the impairment of the same forms of memory are present, amnesia can develop in different ways. Impairment of memory reconsolidation in the conditioned food aversion model through both the serotonin receptor antagonist and the antagonist of NMDA glutamate
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Another interesting interaction concerns NMDA
2023-09-04

Another interesting interaction concerns NMDA preconditioning to protect against glutamate neurotoxicity. It has been shown that an A1R antagonist prevented neuroprotection evoked by NMDA preconditioning against glutamate-induced cellular damage in cerebellar granule cells. In this study, the functi
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br Effective therapeutic window of AR actions
2023-09-04

Effective therapeutic window of AR actions on ROP Retinal vasculature undergoes critical developmental changes postnatally: from P7 onward the superficial orexin mg start sprouting vertically in retina to form first the deep then the intermediated vascular plexus in the retina of C57BL/6 mice (Sm
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A more versatile cellular delivery system
2023-09-04

A more versatile cellular delivery system for adenosine was generated by engineering mouse embryonic stem cells to lack both ionomycin australia of Adk (Fedele et al., 2004). Using a step-wise differentiation protocol (Okabe et al., 1996) Adk−/− ES cells were differentiated into transplantable aden
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br Experimental section br Results and discussion
2023-09-04

Experimental section Results and discussion Conclusion Acknowledgements This work was financially supported by Recruitment Program of Global Experts, and the Director Foundation of XTIPC, CAS, Grant No. 2015RC011. This work was also financially supported by Natural Science Foundation of
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The lanthanide series of chemical elements comprises
2023-09-04

The lanthanide series of chemical elements comprises the fifteen metallic chemical elements with atomic numbers 57 through 71, from lanthanum to lutetium. Though originally described as ‘‘rare earths’’ because of their natural occurrence as metal oxides, they are not particularly rare. The lanthanid
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Several mechanisms have been suggested
2023-09-01

Several mechanisms have been suggested to account for the causal association of ICAM-1 induction and leukocyte adhesion with DR, including oxidative stress [16], NF-κB [17], PKC [18], and bioactive lipids [19]. Our previous studies highlighted the role of bioactive lipid metabolites derived from 12/
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Receptor Subtypes and Their Function Critical
2023-09-01

Receptor Subtypes and Their Function – Critical Appraisal Largely unselective ligands of the benzodiazepine binding site, such as diazepam, are known to elicit a wide range of in vivo effects including hypnosis, sedation, anxiolysis, and muscle relaxation. Genetically modified mice were introduced
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br Concluding remarks The past decade
2023-09-01

Concluding remarks The past decade has seen rapid advances in our understanding of the metabolic reprogramming that occurs during tumorigenesis. Strategies to target specific nodes of cancer cell amino Epigallocatechin synthesis metabolism have progressed from preclinical studies to clinical tri
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br Concluding remarks The past decade
2023-09-01

Concluding remarks The past decade has seen rapid advances in our understanding of the metabolic reprogramming that occurs during tumorigenesis. Strategies to target specific nodes of cancer cell amino Ellipticine metabolism have progressed from preclinical studies to clinical trials, and are sho
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Previous studies to investigate the functions of AHR in Treg
2023-09-01

Previous studies to investigate the functions of AHR in Treg Poziotinib have employed a loss-of-function approach, using AHR complete-null mice, or a gain-of-function approach by ligand administration. However, these approaches may confound the interpretation of the results. For example, the broad e
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Polycyclic aromatic hydrocarbons PAHs are
2023-09-01

Polycyclic aromatic hydrocarbons (PAHs) are abundant environmental contaminants that are produced by the incomplete combustion of organic matter, combustion engines, residential heating, PG 01037 dihydrochloride burning, and industrial activities (Gelboin, 1980; Phillips, 1999, Phillips, 2002). Som
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br Materials and methods br Results br Discussion br
2023-09-01

Materials and methods Results Discussion Conclusions These studies provide important mechanistic insights to explain the long-established physiological observation that obese adipose tissue has higher rates of basal lipolysis. Increased lipolysis contributes to increased hepatic Chrysin
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AR-A014418 In our previous study adiponectin system genes an
2023-09-01

In our previous study, adiponectin system (genes and proteins) expression in the porcine endometrium and myometrium was observed on Days 2 to 3, 10 to 12, 14 to 16, and 17 to 19 of the estrous cycle [23]. Adiponectin receptors expression (mRNA) in the porcine endometrium was described by Lord et al.
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In conclusion the results of this investigation suggest that
2023-09-01

In conclusion, the results of this investigation suggest that the involvement of PGE2 in the pathogenesis of pulpal inflammation and repair may be related to its induction of cAMP production. PGE2-induced cAMP production in dental pulp cells is mediated by binding to the EP2 receptor, activation of
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