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br OPG RANK and RANKL contribute to the
2019-06-27
OPG, RANK and RANKL contribute to the vicious cycle established between tumour Lidocaine and bone microenvironment: evidences for sarcomas and carcinomas RANK/RANKL axis is involved in the tumorigenic process RANK/RANKL axis is associated with the bone metastastic process, and as several argu
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Depending on the target gene KLF
2019-06-27
Depending on the target gene, KLF4 may function as both a repressor and activator of transcription [31,32]. Previous studies demonstrated Bax could be a tumor-suppressor target of KLF4 functioning as an anti-oncogene [33,34]. When transfected with anti-miR-367, MG-63 and U2OS BIX 02565 showed enhan
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A dual chamber ICD was then
2019-06-27
A dual-chamber ICD was then implanted and the optimal atrioventricular (AV) interval to obtain the lowest PG was adjusted to a sensed PV interval of 70ms/AV pace of 60ms using echocardiography. After 1 week, the LVOT-PG had decreased to 68mmHg (Fig. 2B); by 3 weeks, it had decreased to 26mmHg (Fig.
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Early repolarization ER is characterized by elevation of the
2019-06-27
Early repolarization (ER) is characterized by elevation of the QRS-ST junction (J point) and QRS notching or slurring (J wave) in multiple leads, especially the inferior and/or left precordial leads. Although this finding has been considered to be a benign ECG manifestation, Haïssaguerre et al repor
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In addition evidence of similar resting HR s before
2019-06-27
In addition, evidence of similar resting HR׳s before exercise in the patients and in the controls implies similar autonomic activity at rest during the daytime in both groups of subjects. In contrast, previous studies have reported changes in the nocturnal HR of BrS patients [3,28]. The discrepancy
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Pramipexole br II En lo que sigue proponemos un an
2019-06-27
II En lo que sigue, proponemos un análisis de El fistol del diablo que parte inicialmente de una etnografía simbólica de objetos de valor estético —caso ilustrado en la novela de Payno con un fistol de diamante engastado—, con raíces en leyendas y en la historia literaria de varias naciones del m
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En toda su trayectoria una
2019-06-27
En toda su trayectoria una constante que ha sido reconocida por la comunidad académica y por él mismo, en diversas ocasiones, fue la de “bautizar los nuevos animales”, la de crear conceptos para fenómenos nuevos que consideró específicos, en el marco de la búsqueda en su última etapa de una teoría d
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Fujimori fei eleito presidente neste contexto cr tico com um
2019-06-27
Fujimori fei eleito presidente neste contexto crítico com uma plataforma que parecia capturar, ao mesmo tempo, o rechaço popular à política criolla personificada em Vargas Llosa, e uma desconfiança em relação às ambiguidades da esquerda, que oscilava entre um passado radical como Sendero ou um futur
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The recently published global consensus recommendations
2019-06-27
The recently published global consensus recommendations on prevention and management of rickets advocate for the eradication of rickets and osteomalacia through implementation of national supplementation and food fortification programmes containing vitamin D, calcium, or both. On the basis of high-q
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Es pertinente mencionar que el
2019-06-26
Es pertinente mencionar que el enfoque metodológico desarrollado por la autora nos adentra en las preocupaciones centrales de estos tres intelectuales; nos presenta sus argumentos, su visión de México, del gobierno, de sus instituciones, su pasado y el devenir. De igual forma, se muestra a estos tre
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br Introducci n Las encendidas palabras de
2019-06-26
Introducción Las encendidas palabras de fray Servando Teresa de Mier provienen del Discurso preliminar que acompaña la reedición de la Brevíssima relación de la destruyción de las Indias de fray Bartolomé de las Casas, publicado en México en 1812. Fray Servando no duda en calificar al dominico, l
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No final dos anos o
2019-06-26
No final dos anos 1960 o apra já estava desalojado da liderança do movimento estudantil, e na década seguinte o apelo guerrilheiro daria lugar clinical trial uma atuação colada aos movimentos camponeses, embora a revolução permanecesse no horizonte político desta esquerda, que se propõe a fundar uma
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En ella se muestran los
2019-06-26
En ella se muestran los criterios sobre los que se acepta negociar en los diálogos de paz en La Habana. Fuera de estas reglas de juego para la negociación, se establecen puntos en común en ella y que según Aira: “Es indiscutible que el ‘Poder’ desempeña un papel fundamental dentro de la negociación”
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Idelalisib demonstrates a dual mechanism of action
2019-06-26
Idelalisib demonstrates a dual mechanism of action by inhibiting pro-survival signalling pathways [6], and, like other kinase inhibitors, leads to re-localisation of tumour VX-661 by blocking ingress into and promoting egress out of the lymph node into the blood. Release from the protective lymph e
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br Conflict of interest br Introduction Garrigue et al
2019-06-26
Conflict of interest Introduction Garrigue et al. reported that atrial overdrive pacing reduces the number of sleep cdc42 pathway episodes in pacemaker patients without heart failure [1]. However, this finding has not been replicated in subsequent investigations [2–5], although some meta-analy
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