• Resveratrol is a phytoalexin that occurs

  2020-02-14

  

  Resveratrol is a phytoalexin that occurs in relatively large amounts in peanut, berries, grapes, and red wine (Soleas et al., 2001). A recent study showed that resveratrol prevents social deficit in an animal model of autism, indicating its potential for possible therapeutic use in children with aut

• Other membrane currents are affected as well

  2020-02-14

  

  Other membrane currents are affected as well. Some studies have provided evidence that sulfonylureas, in addition to blocking KATP channels, also inhibit chloride and calcium channels. GLYB has been shown to almost inhibit the current generated by Na+–K+ pumps in a concentration-dependent manner (wi

• br Materials and methods br Results br Discussion

  2020-02-14

  

  Materials and methods Results Discussion In particular, we showed that pancreatic neuroendocrine tumor cystamine recognize cAMP as a stimulatory signal for cell proliferation. Conversely, cAMP was found to have an inhibitory effect on cell proliferation in bronchial carcinoids cells. The d

• br Acknowledgements This research was supported by Slovenian

  2020-02-14

  

  Acknowledgements This research was supported by Slovenian Research Agency (ARRS). We thank prof. R. Marinšek Logar for helpful advice, Dr. T. Kranjc for help with data management, N. Vrhovnik and G. Lavrič for technical help with preliminary growth experiments and dr. J. Burkeljca for help with g

• Although the formation and toxicity of DPC is theoretically

  2020-02-13

  

  Although the formation and toxicity of DPC is theoretically acceptable, it is difficult to evaluate the specific role of DPC and its repair enzyme MGMT in the cytotoxic and mutagenic effects because DPCs are estimated to constitute only 1%–3% of total DNA damage when carboxypeptidase a are exposed

• LPA is known to regulate the

  2020-02-13

  

  LPA is known to regulate the peroxisome proliferator-activated receptor γ and the reorganization of actin cytoskeleton [58]. However, the physiological functions of LPA in cells are still poorly understood. The simultaneous production of PA with/without 1-LPA or 2-LPA may be important to maximize a

• Recent studies have shown arsenic could cause

  2020-02-13

  

  Recent studies have shown arsenic could cause autophagic cell death in malignant cells, including leukemia and malignant glioma mlck synthesis [16], [17]. However, at present, little is known about the consequences of arsenic-treated urothelial cells in autophagy and expression of its related prote

• Prostaglandins production and some of their possible biologi

  2020-02-13

  

  Prostaglandins production and some of their possible biological functions have been reported in protozoa, helminths, and fungi organisms, for example amphizoic amoebas of the genus Acanthamoeba and Entamoeba (E. histolytica) produce PGA2, PGE2 and PGF2α [5,6]. PGA2 is believed to be an intrinsic osm

• br Acknowledgements br Introduction In Arabidopsis thaliana

  2020-02-13

  

  Acknowledgements Introduction In Arabidopsis thaliana (L.) Heynh, there are at least four copies of the caseine kinase-like gene Ck1, which is involved in peptide phosphorylation in mammals [1]. These genes are distributed on Famprofazone australia 1, 2, 4, and 5. A similar number of copies fo

• br Author contributions br Funding M E B

  2020-02-13

  

  Author contributions Funding M.E.B. was supported by Research Fund #3096. Competing interests Introduction Lung cancer has become one of the most common death causes in both male and female malignant tumors (Jemal et al., 2011). Air pollution, smoking and estrogen level are known risk f

• Binding affinity was measured by a scintillation

  2020-02-13

  

  Binding affinity was measured by a scintillation proximity binding assay using [H]4-OHT (ERRγ) or [H]estradiol (ERα/β) as radioligand. In all cases, the ERβ affinity was not significantly different from ERα. Compounds were compared to , which showed high affinity for both receptors and moderate (six

• The UPP broadly involves proteolysis in biochemical processe

  2020-02-13

  

  The UPP broadly involves proteolysis in biochemical processes and is a potential target for cancer therapy. The UPP degrades unfolding or damaged proteins by an ATP-dependent mechanism (Ciechanover, Elias, Heller, Ferber, & Hershko, 1980). It also plays an important role in Valproic acid australia r

• The enzymatic activity of recombinant

  2020-02-13

  

  The enzymatic activity of recombinant sponge P4H was assayed in vitro both at 37°C, the standard enzymatic kinetics temperature, and at 15°C, the typical sea temperature of C. reniformis marine environment (Fig. 2C). Surprisingly the data obtained indicate that the sponge enzyme has a lower activity

• A-366 mg br Discussion We are reporting a cryptic

  2020-02-13

  

  Discussion We are reporting a cryptic insertion of chromosome 22 material (EWS) to the long arm of chromosome 11 (11q24, FLI-1) recognizable by FISH in A-366 mg exhibiting trisomy 8 as the sole cytogenetic anomaly. In ES and PNET tumors, trisomy 8 is the most common secondary abnormality [6]. Add

• The activity of cysteine endopeptidases involved in the germ

  2020-02-12

  

  The activity of cysteine endopeptidases involved in the germination of caryopses is generally regulated at two levels: the hormonal induction of synthesis by gibberellins (Drzymała et al., 2008) and a putative regulation of activity by phytocystatines (Kiyosaki et al., 2007, Martinez et al., 2009),

15445 records 871/1030 page Previous Next First page 上5页 871872873874875 下5页 Last page