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Introduction Neuroblastoma NB which arises from embryonal ne
2019-06-26
Introduction Neuroblastoma (NB), which arises from embryonal neural crest cells, is the most common extra-cranial solid tumor of childhood and accounts for more than 15% of all child cancer death [1,2]. Patients with NB frequently manifest disseminated disease at first visit and prognosis of these
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br Predictors of benefit from bisphosphonates Randomized con
2019-06-26
Predictors of benefit from bisphosphonates Randomized control studies of adjuvant BP therapy in early breast cancer show benefit related to “low estrogen states” [1,2,5,6]. Unfortunately, thus far, only one study has assessed systemic estrogen levels to substantiate these results. This is clearly
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In the past decade preclinical
2019-06-26
In the past decade, preclinical studies have addressed the putative role of non-coding RNAs in tumorigenesis, metastasis and therapy response in osteotropic cancers. Besides long non-coding RNAs, microRNAs (miRs) represent a class of small non-coding RNAs, (18–25 nucleotides long), that regulate pro
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br Discussion We describe an additional diagnosis
2019-06-26
Discussion We describe an additional diagnosis to consider when BVT is identified. One of the proposed mechanisms of BVT include elevated intracellular calcium, causing delay after depolarization in anatomically separate parts of the conducting system. Baher et al. [1] proposed that two separate
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Tobacco use is poised to kill
2019-06-26
Tobacco use is poised to kill as many as 1 billion people in the 21st century, primarily from non-communicable diseases. Less often noted is the effect of tobacco use and second-hand smoke exposure on maternal and child health. Cigarette smoking during pregnancy poses serious risk to the mother and
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La eleg a de tus ojos Uno de los poemas
2019-06-25
“La elegía de tus ojos” (1914) Uno de los poemas más tempranos de Pellicer, “La elegía de tus ojos”, ya demuestra un sentido nuevo de historicidad. Escrito en 1914, en el apogeo del posmodernismo y durante la Revolución mexicana, cuando el poeta tenía apenas unos quince años, este poema se adhiere
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More recently primary tumor driven
2019-06-25
More recently, primary tumor driven generation of a bone pre-metastatic niche was observed in a mouse model of estrogen receptor-negative breast cancer metastasis. Specifically, lysyl oxidase (LOX) secreted into the circulation from hypoxic primary breast tumors disrupted bone homeostasis, thereby i
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Uno de los poemas extensos de
2019-06-25
Uno de los poemas extensos de Paz, que muestra con perfección esta poética de la estructuración espacial es “Vuelta”, publicado por primera vez, en forma suelta, al retorno del poeta Bardoxolone methyl of México en 1971, e incluido después en el poemario de mismo nombre ( 1976). En unas de las págin
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A coleta de dados para pesquisa ocorreu
2019-06-25
A coleta de dados para pesquisa ocorreu com diversas técnicas. In-vestigações em endereços eletrônicos, jornais, revistas, livros, artigos. En trevistas pessoalmente, por telefone e emails. Os autores também mantiveram contato via correspondências com todas as organizações relacionadas no Quadro 1 e
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XL228 Aside from this report only two
2019-06-25
Aside from this report, only two other studies of dexrazoxane use in adult AML patients have been published. In a series of seven patients with AML, Lemez and Maresova reported that the administration of dexrazoxane 30min before daunorubicin (dose 8-13x higher than daunorubicin) or mitoxantrone (dos
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br Acknowledgments br Introduction Since the first
2019-06-25
Acknowledgments Introduction Since the first hospice was established in the United Kingdom in the late 1960s, the use of hospice and palliative care has become popular worldwide. In developed countries, hospice and palliative care are now used for services ranging from in-patient to community/
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En la presentaci n del volumen Edgardo
2019-06-24
En la presentación del volumen, Edgardo Lander explica que la implantación del neoliberalismo como pensamiento único dificultaba vislumbrar y formular alternativas epistemológicas y de intervención intelectual. De esta manera, el libro apuesta 10Panx rastrear la genealogía de este pensamiento, ident
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Chronic hepatitis B virus HBV infection is prevalent in many
2019-06-24
Chronic pak1 virus (HBV) infection is prevalent in many Asian countries, notwithstanding three decades of universal hepatitis B vaccination programs. The invention of nucleos(t)ide analogs (NUCs) was a breakthrough in the treatment of chronic hepatitis B (CHB). However, HBV continues to be a challen
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br Conclusions br Financial support br Conflict
2019-06-24
Conclusions Financial support Conflict of interest Acknowledgment Introduction Cardiac resynchronization therapy (CRT) has been demonstrated to improve symptoms, quality of life, functional status, and reduce mortality and GSK180 failure-related hospitalizations in patients with New
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br Disclosures br Acknowledgments br Introduction
2019-06-24
Disclosures Acknowledgments Introduction Long-term endurance sports have recently been recognized as one of the risk factors for atrial fibrillation (AF) [1–8]; widely accepted risk factors for AF include age, hypertension, diabetes mellitus, structural INCB3344 weight disease, hyperthyroi
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